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Unit on Molecular Recognition and Assembly
 
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Hydration Changes Linked to Sequence Specific DNA-Protein Recognition Reactions

Colombo, M.F., Rau, D.C., and Parsegian, V.A.: Protein solvation in allosteric regulation: A water effect on hemoglobin. Science 256: 655-659, 1992. [PDF]

Garner, M.M., and Rau, D.C.: Water release associated with specific binding of gal repressor. The EMBO J. 14: 1257-1263, 1995.

Sidorova, N.Yu., and Rau, D.C.: Differences in water release for the binding of EcoRI to specific and nonspecific DNA sequences. Proc. Natl. Acad. Sci. USA, 93: 12272-12277, 1996. [PDF]

Parsegian, V.A., Rand, R.P., and Rau, D.C.: Osmotic stress, crowding, preferential hydration, and binding: A comparison of perspectives. Proc. Natl. Acad. Sci. USA, 97: 3987-3992, 2000. [PDF]

Sidorova, N.Y., and Rau, D.C.: Linkage of EcoRI dissociation from its specific DNA recognition site to water activity, salt concentration, and pH: Separating their roles in specific and nonspecific binding. J. Molecular Biology, 310: 801-816, 2001. [PDF]

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